Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C000632
6 activity records2 related patents
2D structure
N#Cc1cc(-c2cccc(Cl)c2)cnc1N1CCC(CNCc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | -57 | % | 10 nM | 24 h | MYC | - | HL-60 | WO2023116835A1 | PGDB_A016640 | PGDB_C000632 | PGDB_AS002563 | View |
| IC50 | - | = | 1 | nM | - | — | - | - | HL-60 | WO2023116835A1 | PGDB_A024396 | PGDB_C000632 | PGDB_AS000718 | View |
| % Degradation | - | = | 97 | % | 10 nM | 24 h | - | - | HL-60 | CN117982498A | PGDB_A051588 | PGDB_C000632 | PGDB_AS001212 | View |
| % Degradation | - | = | -57 | % | 10 nM | - | - | - | HL-60 | CN117982498A | PGDB_A054434 | PGDB_C000632 | PGDB_AS001270 | View |
| IC50 | - | = | 1 | nM | - | — | - | - | HL-60 | CN117982498A | PGDB_A063455 | PGDB_C000632 | PGDB_AS001350 | View |
| % Degradation | - | = | 97 | % | 10 nM | 24 h | GSPT1 | - | HL-60 | WO2023116835A1 | PGDB_A066728 | PGDB_C000632 | PGDB_AS000871 | View |