Assignee profile

Plexium

Coverage of patents, compounds and activity records linked to this assignee.

10 patents1,054 compounds5,388 activity records
Summary
AssigneePlexium
Filing years2021-2025
Patents10
Compounds1,054
Activity records5,388
Patent families10
Targets8
Assay familiesbinding, cellular_function, degradation
Activity metricsDC50, Dmax, EC50, IC50, degradation, target_engagement
Overview

Target distribution and active-compound trend

Target distribution

5,376 activity records

8 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

023547020212023202420252026
Activity compounds and values

Activity records

5,376 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C000416
EC50-=0.026uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A007974PGDB_C000416PGDB_AS001328View
2D structure for PGDB_C000471
EC50-=0.014uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A008065PGDB_C000471PGDB_AS001328View
2D structure for PGDB_C000432
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A008149PGDB_C000432PGDB_AS001328View
2D structure for PGDB_C000430
% Degradation-=48.8%--IKZF2CRBNHEK293TAR126418A1PGDB_A008160PGDB_C000430PGDB_AS000416View
2D structure for PGDB_C000388
DC50-=0.005uM-—IKZF2-HEK293TAR126418A1PGDB_A009740PGDB_C000388PGDB_AS001753View
2D structure for PGDB_C000403
% Degradation-<15%--IKZF2CRBNHEK293TAR126418A1PGDB_A010123PGDB_C000403PGDB_AS000416View
2D structure for PGDB_C000449
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A010176PGDB_C000449PGDB_AS001328View
2D structure for PGDB_C000408
EC50-=0.011uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A010779PGDB_C000408PGDB_AS001328View
2D structure for PGDB_C000462
EC50-=0.006uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A010818PGDB_C000462PGDB_AS001328View
2D structure for PGDB_C000419
EC50-=0.037uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A011234PGDB_C000419PGDB_AS001328View
2D structure for PGDB_C000460
EC50-=0.008uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A011396PGDB_C000460PGDB_AS001328View
2D structure for PGDB_C000388
% Degradation-=82.1%--IKZF2-HEK293TAR126418A1PGDB_A011731PGDB_C000388PGDB_AS002452View
2D structure for PGDB_C000416
% Degradation-=42.5%--IKZF2CRBNHEK293TAR126418A1PGDB_A012335PGDB_C000416PGDB_AS000416View
2D structure for PGDB_C000380
DC50->30uM-—IKZF3-HEK293TAR126418A1PGDB_A012563PGDB_C000380PGDB_AS000004View
2D structure for PGDB_C000402
EC50-=0.011uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A013183PGDB_C000402PGDB_AS001328View
2D structure for PGDB_C000437
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A013506PGDB_C000437PGDB_AS001328View
2D structure for PGDB_C000440
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A014063PGDB_C000440PGDB_AS001328View
2D structure for PGDB_C000409
EC50-=0.015uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A014314PGDB_C000409PGDB_AS001328View
2D structure for PGDB_C000399
% Degradation-=86.7%--IKZF2CRBNHEK293TAR126418A1PGDB_A014928PGDB_C000399PGDB_AS000416View
2D structure for PGDB_C000396
EC50-=0.042uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A015449PGDB_C000396PGDB_AS001328View
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