Summary
AssigneePu Meirui Suzhou Biotechnology
Filing years2025
Patents1
Compounds38
Activity records47
Patent families1
Targets1
Assay familiesdegradation, viability
Activity metricsIC50, degradation
Overview

Target distribution and active-compound trend

Target distribution

47 activity records

1 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

019382025
Activity compounds and values

Activity records

47 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C000715
% Degradation-=40-60%--GSPT1-MV-4-11CN120289428APGDB_A007304PGDB_C000715PGDB_AS000838View
2D structure for PGDB_C000732
% Degradation-=40-60%--GSPT1-MV-4-11CN120289428APGDB_A008966PGDB_C000732PGDB_AS000838View
2D structure for PGDB_C000702
% Degradation-=40-60%--GSPT1-MV-4-11CN120289428APGDB_A009112PGDB_C000702PGDB_AS000838View
2D structure for PGDB_C000708
% Degradation-=60-80%--GSPT1-MV-4-11CN120289428APGDB_A009231PGDB_C000708PGDB_AS000838View
2D structure for PGDB_C000711
% Degradation-=60-80%--GSPT1-MV-4-11CN120289428APGDB_A009287PGDB_C000711PGDB_AS000838View
2D structure for PGDB_C000719
% Degradation-=40-60%--GSPT1-MV-4-11CN120289428APGDB_A010308PGDB_C000719PGDB_AS000838View
2D structure for PGDB_C000700
% Degradation-=80-100%--GSPT1-MV-4-11CN120289428APGDB_A011160PGDB_C000700PGDB_AS000838View
2D structure for PGDB_C000716
IC50-=<= 3nM-GSPT1-MV-4-11CN120289428APGDB_A013490PGDB_C000716PGDB_AS002456View
2D structure for PGDB_C000725
IC50-=<= 3nM-GSPT1-MV-4-11CN120289428APGDB_A015530PGDB_C000725PGDB_AS002456View
2D structure for PGDB_C000714
% Degradation-=60-80%--GSPT1-MV-4-11CN120289428APGDB_A016068PGDB_C000714PGDB_AS000838View
2D structure for PGDB_C000733
% Degradation-=20-40%--GSPT1-MV-4-11CN120289428APGDB_A019537PGDB_C000733PGDB_AS000838View
2D structure for PGDB_C000717
% Degradation-=40-60%--GSPT1-MV-4-11CN120289428APGDB_A020379PGDB_C000717PGDB_AS000838View
2D structure for PGDB_C000708
IC50-=> 3-5nM-GSPT1-MV-4-11CN120289428APGDB_A021538PGDB_C000708PGDB_AS002456View
2D structure for PGDB_C000707
IC50-=> 20-30nM-GSPT1-MV-4-11CN120289428APGDB_A028240PGDB_C000707PGDB_AS002456View
2D structure for PGDB_C000727
% Degradation-=80-100%--GSPT1-MV-4-11CN120289428APGDB_A030058PGDB_C000727PGDB_AS000838View
2D structure for PGDB_C000731
% Degradation-=60-80%--GSPT1-MV-4-11CN120289428APGDB_A031714PGDB_C000731PGDB_AS000838View
2D structure for PGDB_C000709
% Degradation-=40-60%--GSPT1-MV-4-11CN120289428APGDB_A032581PGDB_C000709PGDB_AS000838View
2D structure for PGDB_C000713
IC50-=> 3-5nM-GSPT1-MV-4-11CN120289428APGDB_A034055PGDB_C000713PGDB_AS002456View
2D structure for PGDB_C000705
% Degradation-=20-40%--GSPT1-MV-4-11CN120289428APGDB_A034170PGDB_C000705PGDB_AS000838View
2D structure for PGDB_C000723
% Degradation-=40-60%--GSPT1-MV-4-11CN120289428APGDB_A036562PGDB_C000723PGDB_AS000838View