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Compound
PGDB_C000361
7 activity records1 related patents
2D structure
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)N1CC(N3CCN(c4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)C1)c1nnc(C)n1-2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-1000 | nM | - | — | BRD4/GSPT1 | - | HL-60 | CN117756818A | PGDB_A007022 | PGDB_C000361 | PGDB_AS001357 | View |
| IC50 | - | = | 100-1000 | nM | - | — | BRD4/GSPT1 | - | Oci-AML3 | CN117756818A | PGDB_A012063 | PGDB_C000361 | PGDB_AS002081 | View |
| % Degradation | - | = | 30-50 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A028615 | PGDB_C000361 | PGDB_AS000622 | View |
| IC50 | - | = | 100-1000 | nM | - | — | - | - | MOLM-13 | CN117756818A | PGDB_A029821 | PGDB_C000361 | PGDB_AS001583 | View |
| IC50 | - | = | 100-1000 | nM | - | — | - | - | THP-1 | CN117756818A | PGDB_A041347 | PGDB_C000361 | PGDB_AS000638 | View |
| IC50 | - | < | 100 | nM | - | — | BRD4/GSPT1 | - | NB4 | CN117756818A | PGDB_A071114 | PGDB_C000361 | PGDB_AS000935 | View |
| % Degradation | - | = | 70-90 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A074805 | PGDB_C000361 | PGDB_AS002573 | View |