Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C000372
7 activity records1 related patents
2D structure
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)N1CCN(CC3CN(c4ccc5c(c4)C(=O)N(C4CCC(=O)NC4=O)C5=O)C3)CC1)c1nnc(C)n1-2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 17.2 | nM | - | — | - | - | MOLM-13 | CN117756818A | PGDB_A036486 | PGDB_C000372 | PGDB_AS001583 | View |
| IC50 | - | < | 100 | nM | - | — | BRD4/GSPT1 | - | Oci-AML3 | CN117756818A | PGDB_A037969 | PGDB_C000372 | PGDB_AS002081 | View |
| % Degradation | - | = | 90-100 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A045658 | PGDB_C000372 | PGDB_AS000622 | View |
| IC50 | - | = | 7.8 | nM | - | — | BRD4/GSPT1 | - | NB4 | CN117756818A | PGDB_A051425 | PGDB_C000372 | PGDB_AS000935 | View |
| IC50 | - | = | 12.4 | nM | - | — | BRD4/GSPT1 | - | HL-60 | CN117756818A | PGDB_A054737 | PGDB_C000372 | PGDB_AS001357 | View |
| IC50 | - | = | 31.96 | nM | - | — | - | - | THP-1 | CN117756818A | PGDB_A061716 | PGDB_C000372 | PGDB_AS000638 | View |
| % Degradation | - | = | 90-100 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A066692 | PGDB_C000372 | PGDB_AS002573 | View |