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Compound
PGDB_C000376
7 activity records1 related patents
2D structure
CC1=C(C)C2C(c3ccc(Cl)cc3)=N[C@@H](CC(=O)N3CCN(C4CCN(c5ccc6c(c5)CN(C5CCC(=O)NC5=O)C6=O)CC4)CC3)c3nnc(C)n3C2S1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 90-100 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A007770 | PGDB_C000376 | PGDB_AS002573 | View |
| IC50 | - | < | 100 | nM | - | — | BRD4/GSPT1 | - | HL-60 | CN117756818A | PGDB_A014248 | PGDB_C000376 | PGDB_AS001357 | View |
| IC50 | - | < | 100 | nM | - | — | BRD4/GSPT1 | - | NB4 | CN117756818A | PGDB_A022109 | PGDB_C000376 | PGDB_AS000935 | View |
| IC50 | - | < | 100 | nM | - | — | - | - | THP-1 | CN117756818A | PGDB_A043326 | PGDB_C000376 | PGDB_AS000638 | View |
| % Degradation | - | = | 90-100 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A051805 | PGDB_C000376 | PGDB_AS000622 | View |
| IC50 | - | < | 100 | nM | - | — | BRD4/GSPT1 | - | Oci-AML3 | CN117756818A | PGDB_A052862 | PGDB_C000376 | PGDB_AS002081 | View |
| IC50 | - | < | 100 | nM | - | — | - | - | MOLM-13 | CN117756818A | PGDB_A057575 | PGDB_C000376 | PGDB_AS001583 | View |