Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C000377
7 activity records1 related patents
2D structure
Cc1nc(Nc2nnc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCOC(=O)[C@H](C)NC(=O)C[C@@H]3N=C(c4ccc(Cl)cc4)c4c(sc(C)c4C)-n4c(C)nnc43)CC2)n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 30 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A009491 | PGDB_C000377 | PGDB_AS002573 | View |
| IC50 | - | > | 2000 | nM | - | — | BRD4/GSPT1 | - | Oci-AML3 | CN117756818A | PGDB_A032790 | PGDB_C000377 | PGDB_AS002081 | View |
| IC50 | - | = | 1000-2000 | nM | - | — | BRD4/GSPT1 | - | NB4 | CN117756818A | PGDB_A034049 | PGDB_C000377 | PGDB_AS000935 | View |
| IC50 | - | = | 100-1000 | nM | - | — | - | - | MOLM-13 | CN117756818A | PGDB_A041840 | PGDB_C000377 | PGDB_AS001583 | View |
| IC50 | - | = | 100-1000 | nM | - | — | BRD4/GSPT1 | - | HL-60 | CN117756818A | PGDB_A050817 | PGDB_C000377 | PGDB_AS001357 | View |
| IC50 | - | > | 2000 | nM | - | — | - | - | THP-1 | CN117756818A | PGDB_A061893 | PGDB_C000377 | PGDB_AS000638 | View |
| % Degradation | - | < | 30 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A065432 | PGDB_C000377 | PGDB_AS000622 | View |