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Compound
PGDB_C000843
8 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CCN(C3CCN(Cc4cccc5c4CN(C4CCC(=O)NC4=O)C5=S)CC3(F)F)CC2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | CN120548310A | PGDB_A008247 | PGDB_C000843 | PGDB_AS001655 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | CN120548310A | PGDB_A010682 | PGDB_C000843 | PGDB_AS000946 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | CN120548310A | PGDB_A025051 | PGDB_C000843 | PGDB_AS001462 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | CN120548310A | PGDB_A026739 | PGDB_C000843 | PGDB_AS001449 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | CN120548310A | PGDB_A027061 | PGDB_C000843 | PGDB_AS002025 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | CN120548310A | PGDB_A040998 | PGDB_C000843 | PGDB_AS000102 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | CN120548310A | PGDB_A053792 | PGDB_C000843 | PGDB_AS001466 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | CN120548310A | PGDB_A069992 | PGDB_C000843 | PGDB_AS002000 | View |