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Compound
PGDB_C000847
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cccc(CN4CCC(N5CC=C(c6cccc(Cl)c6Cl)CC5)C(F)(F)C4)c3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 53-60 | % | 2 uM | - | CRBN | CRBN | - | CN120548310A | PGDB_A015336 | PGDB_C000847 | PGDB_AS001462 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | CN120548310A | PGDB_A016024 | PGDB_C000847 | PGDB_AS000946 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | CN120548310A | PGDB_A017769 | PGDB_C000847 | PGDB_AS000102 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | CN120548310A | PGDB_A022592 | PGDB_C000847 | PGDB_AS001449 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | CN120548310A | PGDB_A051231 | PGDB_C000847 | PGDB_AS001655 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | CN120548310A | PGDB_A055933 | PGDB_C000847 | PGDB_AS001466 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | CN120548310A | PGDB_A058816 | PGDB_C000847 | PGDB_AS002025 | View |
| % Inhibition | - | = | 30-40 | % | 0.5 uM | - | CRBN | CRBN | - | CN120548310A | PGDB_A070268 | PGDB_C000847 | PGDB_AS002000 | View |