Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C001465
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(COC(=O)Nc4ccc(C(F)(F)F)c(C#CC5CC5)c4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 25.4 | nM | - | — | GSPT1 | - | NCI-H1155 | CN118852145A | PGDB_A015479 | PGDB_C001465 | PGDB_AS001039 | View |
| Dmax | - | = | 93.8 | % | Concentration series: 1 uM | 24 h | GSPT1 | - | HEK293 | CN118852145A | PGDB_A021184 | PGDB_C001465 | PGDB_AS002339 | View |
| IC50 | - | = | 577.69 | nM | - | — | CRBN | CRBN | - | CN118852145A | PGDB_A054019 | PGDB_C001465 | PGDB_AS000570 | View |
| DC50 | - | = | 4.09 | nM | - | — | GSPT1 | - | HEK293 | CN118852145A | PGDB_A056822 | PGDB_C001465 | PGDB_AS001853 | View |