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Compound
PGDB_C001470
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(COC(=O)Nc4ccc(C#CC5CC5)c(Cl)c4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 322.59 | nM | - | — | CRBN | CRBN | - | CN118852145A | PGDB_A017444 | PGDB_C001470 | PGDB_AS000570 | View |
| Dmax | - | = | 93.56 | % | Concentration series: 1 uM | 24 h | GSPT1 | - | HEK293 | CN118852145A | PGDB_A024704 | PGDB_C001470 | PGDB_AS002339 | View |
| DC50 | - | = | 1.67 | nM | - | — | GSPT1 | - | HEK293 | CN118852145A | PGDB_A069918 | PGDB_C001470 | PGDB_AS001853 | View |
| IC50 | - | = | 15.9 | nM | - | — | GSPT1 | - | NCI-H1155 | CN118852145A | PGDB_A071569 | PGDB_C001470 | PGDB_AS001039 | View |