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Compound
PGDB_C001475
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(cc(COC(=O)Nc4ccc(Cl)c(C#CC5CC5)c4)cc3C3CC3)C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 316.86 | nM | - | — | CRBN | CRBN | - | CN118852145A | PGDB_A008335 | PGDB_C001475 | PGDB_AS000570 | View |
| Dmax | - | = | 89.86 | % | Concentration series: 1 uM | 24 h | GSPT1 | - | HEK293 | CN118852145A | PGDB_A025473 | PGDB_C001475 | PGDB_AS002339 | View |
| IC50 | - | = | 20.4 | nM | - | — | GSPT1 | - | NCI-H1155 | CN118852145A | PGDB_A071761 | PGDB_C001475 | PGDB_AS001039 | View |
| DC50 | - | = | 5 | nM | - | — | GSPT1 | - | HEK293 | CN118852145A | PGDB_A073744 | PGDB_C001475 | PGDB_AS001853 | View |