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Compound
PGDB_C001859
4 activity records1 related patents
2D structure
Cn1cc(-c2cccnc2[C@@H](NC(=O)c2ccc3c(c2)CN([C@H]2CCC(=O)NC2=O)C3=O)C2CCC2)cn1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 0.0741 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A021074 | PGDB_C001859 | PGDB_AS001868 | View |
| IC50 | - | = | 0.024 | uM | - | — | CSNK1A1 | - | MV-4-11 | WO2022257897A1 | PGDB_A030053 | PGDB_C001859 | PGDB_AS000623 | View |
| Dmax | - | = | 72.4 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A066521 | PGDB_C001859 | PGDB_AS000920 | View |
| Dmax | - | = | 15.2 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A074317 | PGDB_C001859 | PGDB_AS000618 | View |