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Compound
PGDB_C001862
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(C(=O)N[C@H](c4ncccc4Cl)C4(F)CCC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 0.279 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A039703 | PGDB_C001862 | PGDB_AS001868 | View |
| IC50 | - | = | 0.133 | uM | - | — | CSNK1A1 | - | MV-4-11 | WO2022257897A1 | PGDB_A044384 | PGDB_C001862 | PGDB_AS000623 | View |
| Dmax | - | = | 59.8 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A050809 | PGDB_C001862 | PGDB_AS000920 | View |
| Dmax | - | = | 25 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A053189 | PGDB_C001862 | PGDB_AS000618 | View |