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Compound
PGDB_C002507
6 activity records1 related patents
2D structure
CC1(C)CCC(CN2CC3CCC(C2)N3Cc2cc3c(cc2F)C(=O)N(C2CCC(=O)NC2=O)C3)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-500 | nM | - | — | - | - | CCRF-CEM | WO2024032689A1 | PGDB_A007318 | PGDB_C002507 | PGDB_AS001396 | View |
| IC50 | - | = | 500-1000 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A027783 | PGDB_C002507 | PGDB_AS001703 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | MV-4-11 | WO2024032689A1 | PGDB_A038375 | PGDB_C002507 | PGDB_AS000885 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A043957 | PGDB_C002507 | PGDB_AS000176 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A047738 | PGDB_C002507 | PGDB_AS000668 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A072633 | PGDB_C002507 | PGDB_AS002239 | View |