Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C002510
5 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CCN(Cc3cc4c(cc3F)C(=O)N(C3CCC(=O)NC3=O)C4)CC2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 500-1000 | nM | - | — | - | - | CCRF-CEM | WO2024032689A1 | PGDB_A007997 | PGDB_C002510 | PGDB_AS001396 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A037775 | PGDB_C002510 | PGDB_AS002239 | View |
| IC50 | - | = | 0.69 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A047372 | PGDB_C002510 | PGDB_AS000095 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A062237 | PGDB_C002510 | PGDB_AS000668 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A062785 | PGDB_C002510 | PGDB_AS000176 | View |