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Compound
PGDB_C002511
6 activity records1 related patents
2D structure
CC1(C)CCC(CN2C3CC2CN(Cc2ccc4c(c2F)CN(C2CCC(=O)NC2=O)C4=O)C3)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A014251 | PGDB_C002511 | PGDB_AS000668 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A023425 | PGDB_C002511 | PGDB_AS001703 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A053850 | PGDB_C002511 | PGDB_AS000176 | View |
| IC50 | - | = | 500-1000 | nM | - | — | - | - | Mino | WO2024032689A1 | PGDB_A057904 | PGDB_C002511 | PGDB_AS001319 | View |
| IC50 | - | = | 0.35 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A059603 | PGDB_C002511 | PGDB_AS000095 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A067531 | PGDB_C002511 | PGDB_AS002239 | View |