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Compound
PGDB_C002542
6 activity records1 related patents
2D structure
Cn1nccc1-c1ccccc1CN1CCN(Cc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-500 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A019281 | PGDB_C002542 | PGDB_AS001703 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A030595 | PGDB_C002542 | PGDB_AS000668 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A042537 | PGDB_C002542 | PGDB_AS002239 | View |
| IC50 | - | = | 0.61 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A043411 | PGDB_C002542 | PGDB_AS000095 | View |
| IC50 | - | = | 500-1000 | nM | - | — | - | - | Mino | WO2024032689A1 | PGDB_A054711 | PGDB_C002542 | PGDB_AS001319 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A069672 | PGDB_C002542 | PGDB_AS000176 | View |