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Compound
PGDB_C002680
4 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CC(=Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A010186 | PGDB_C002680 | PGDB_AS002239 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A022196 | PGDB_C002680 | PGDB_AS000176 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A051554 | PGDB_C002680 | PGDB_AS000668 | View |
| IC50 | - | = | 0.73 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A060045 | PGDB_C002680 | PGDB_AS000095 | View |