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Compound
PGDB_C002738
4 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CCN(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C(C(F)(F)F)C2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A018346 | PGDB_C002738 | PGDB_AS000668 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A039895 | PGDB_C002738 | PGDB_AS000176 | View |
| IC50 | - | = | 0.76 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A056244 | PGDB_C002738 | PGDB_AS000095 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A060198 | PGDB_C002738 | PGDB_AS002239 | View |