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Compound
PGDB_C002744
4 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CC3CN(Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3C2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A012660 | PGDB_C002744 | PGDB_AS002239 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A032608 | PGDB_C002744 | PGDB_AS000176 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A043598 | PGDB_C002744 | PGDB_AS000668 | View |
| IC50 | - | = | 0.74 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A063762 | PGDB_C002744 | PGDB_AS000095 | View |