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Compound
PGDB_C005306
4 activity records1 related patents
2D structure
Cc1ccc([C@H](NC(=O)OC(C)(C)C)C(=O)NCc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 82 | % | 100 nM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A022723 | PGDB_C005306 | PGDB_AS002119 | View |
| IC50 | - | = | 11.3 | nM | - | — | GSPT1 | - | HNT-34 | WO2023078410A1 | PGDB_A041127 | PGDB_C005306 | PGDB_AS000001 | View |
| IC50 | - | = | 12.8 | nM | - | — | GSPT1 | - | HL-60 | WO2023078410A1 | PGDB_A044402 | PGDB_C005306 | PGDB_AS002047 | View |
| % Degradation | - | = | 93 | % | 10 uM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A055125 | PGDB_C005306 | PGDB_AS000305 | View |