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Compound
PGDB_C005326
4 activity records1 related patents
2D structure
CC(C)(C)OC(=O)N[C@H](C(=O)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O)C1CCCC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 7.5 | nM | - | — | GSPT1 | - | HNT-34 | WO2023078410A1 | PGDB_A031614 | PGDB_C005326 | PGDB_AS000001 | View |
| % Degradation | - | = | 98.1 | % | 10 uM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A040795 | PGDB_C005326 | PGDB_AS000305 | View |
| IC50 | - | = | 15 | nM | - | — | GSPT1 | - | HL-60 | WO2023078410A1 | PGDB_A041147 | PGDB_C005326 | PGDB_AS002047 | View |
| % Degradation | - | = | 75 | % | 100 nM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A064447 | PGDB_C005326 | PGDB_AS002119 | View |