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Compound
PGDB_C005355
5 activity records1 related patents
2D structure
CC(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 77.7 | % | 100 nM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A015736 | PGDB_C005355 | PGDB_AS002119 | View |
| IC50 | - | = | 18.6 | nM | - | — | GSPT1 | - | HL-60 | WO2023078410A1 | PGDB_A027253 | PGDB_C005355 | PGDB_AS002047 | View |
| IC50 | - | = | 21.3 | nM | - | — | GSPT1 | - | HNT-34 | WO2023078410A1 | PGDB_A034275 | PGDB_C005355 | PGDB_AS000001 | View |
| % Degradation | - | = | 95.7 | % | 10 uM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A054027 | PGDB_C005355 | PGDB_AS000305 | View |
| IC50 | - | = | 0.6 | nM | - | — | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A064307 | PGDB_C005355 | PGDB_AS001490 | View |