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Compound
PGDB_C008040
4 activity records1 related patents
2D structure
Cn1ccc2cccc(C3CC(OC(=O)NCc4ccc5c(c4)C(=O)N(C4CCC(=O)NC4=O)C5)C3)c21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.021 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A017157 | PGDB_C008040 | PGDB_AS000958 | View |
| IC50 | - | = | 0.11 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A034823 | PGDB_C008040 | PGDB_AS000366 | View |
| Dmax | - | = | 38 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A052525 | PGDB_C008040 | PGDB_AS000735 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A063723 | PGDB_C008040 | PGDB_AS002508 | View |