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Compound
PGDB_C008043
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)O[C@H]4C[C@H](c5cccc6scnc65)C4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 20 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A021601 | PGDB_C008043 | PGDB_AS000735 | View |
| IC50 | - | = | 0.31 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A027569 | PGDB_C008043 | PGDB_AS000366 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A033125 | PGDB_C008043 | PGDB_AS002508 | View |
| IC50 | - | = | 0.078 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A037728 | PGDB_C008043 | PGDB_AS000958 | View |