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Compound
PGDB_C008166
7 activity records1 related patents
2D structure
Cc1cccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)c1OC(F)(F)FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 68.4 | nM | - | — | GSPT1 | - | HEK293 | IL323841A | PGDB_A008332 | PGDB_C008166 | PGDB_AS002492 | View |
| IC50 | - | = | 18.3 | nM | - | — | GSPT1 | - | HL-60 | IL323841A | PGDB_A025621 | PGDB_C008166 | PGDB_AS000799 | View |
| IC50 | - | = | 15.7 | nM | - | — | GSPT1 | - | NCI-H1155 | IL323841A | PGDB_A032825 | PGDB_C008166 | PGDB_AS000925 | View |
| DC50 | - | = | 318 | nM | - | — | GSPT1 | - | HEK293 | IL323841A | PGDB_A034929 | PGDB_C008166 | PGDB_AS000381 | View |
| IC50 | - | = | 18 | nM | - | — | GSPT1 | - | HL-60 | IL323841A | PGDB_A042956 | PGDB_C008166 | PGDB_AS002473 | View |
| IC50 | - | = | 17.7 | nM | - | — | GSPT1 | - | NCI-H1155 | IL323841A | PGDB_A044703 | PGDB_C008166 | PGDB_AS002011 | View |
| Dmax | - | = | 72.9 | % | Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM | 72 h | GSPT1 | - | HEK293 | IL323841A | PGDB_A068557 | PGDB_C008166 | PGDB_AS002464 | View |