Assay

PGDB_AS002464

System: cell_basedTarget: GSPT1Cell line: HEK293
Assay context summary

Assay context

22 activity records
Assay family% Degradation
Systemcell_based
ReadoutDmax
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens
Technologyluminescence
Detection targetprotein_degradation
Activity compounds and values

Activity records

22 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C008158
Dmax-=18%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A013652PGDB_C008158PGDB_AS002464View
2D structure for PGDB_C008153
Dmax-=88.6%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A014822PGDB_C008153PGDB_AS002464View
2D structure for PGDB_C008164
Dmax-=76.5%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A015153PGDB_C008164PGDB_AS002464View
2D structure for PGDB_C008156
Dmax-=37.3%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A015838PGDB_C008156PGDB_AS002464View
2D structure for PGDB_C008157
Dmax-=86.7%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A016391PGDB_C008157PGDB_AS002464View
2D structure for PGDB_C008165
Dmax-=88.3%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A021524PGDB_C008165PGDB_AS002464View
2D structure for PGDB_C008162
Dmax-=55.3%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A022709PGDB_C008162PGDB_AS002464View
2D structure for PGDB_C008167
Dmax-=81.9%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A025689PGDB_C008167PGDB_AS002464View
2D structure for PGDB_C008161
Dmax-=71.4%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A030109PGDB_C008161PGDB_AS002464View
2D structure for PGDB_C008149
Dmax-=78.4%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A030795PGDB_C008149PGDB_AS002464View
2D structure for PGDB_C008163
Dmax-=70.5%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A035863PGDB_C008163PGDB_AS002464View
2D structure for PGDB_C008159
Dmax-=58%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A037437PGDB_C008159PGDB_AS002464View
2D structure for PGDB_C008152
Dmax-=73.3%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A041799PGDB_C008152PGDB_AS002464View
2D structure for PGDB_C008151
Dmax-=79.9%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A044714PGDB_C008151PGDB_AS002464View
2D structure for PGDB_C008154
Dmax-=28.1%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A046975PGDB_C008154PGDB_AS002464View
2D structure for PGDB_C008160
Dmax-=46.2%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A047155PGDB_C008160PGDB_AS002464View
2D structure for PGDB_C001361
Dmax-=78.3%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A050191PGDB_C001361PGDB_AS002464View
2D structure for PGDB_C008155
Dmax-=49.6%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A064845PGDB_C008155PGDB_AS002464View
2D structure for PGDB_C019545
Dmax-=42.8%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A067882PGDB_C019545PGDB_AS002464View
2D structure for PGDB_C008166
Dmax-=72.9%Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM72 hGSPT1-HEK293IL323841APGDB_A068557PGDB_C008166PGDB_AS002464View
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