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Compound
PGDB_C008709
10 activity records2 related patents
2D structure
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4NC4CCC(F)(F)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 98 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A020664 | PGDB_C008709 | PGDB_AS000211 | View |
| EC50 | - | = | 0.01 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A024150 | PGDB_C008709 | PGDB_AS001535 | View |
| % Degradation | - | = | 0.52 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A031596 | PGDB_C008709 | PGDB_AS000906 | View |
| EC50 | - | > | 30 | mM | - | — | IKZF1 | - | 293GT | KR20210031680A | PGDB_A033364 | PGDB_C008709 | PGDB_AS002284 | View |
| EC50 | - | > | 10 | uM | - | — | SALL4 | - | HEK293 | JP2026020265A | PGDB_A044753 | PGDB_C008709 | PGDB_AS001573 | View |
| EC50 | - | = | 0.017 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A046738 | PGDB_C008709 | PGDB_AS001524 | View |
| EC50 | - | = | 0.008 | mM | - | — | IKZF2 | - | 293GT | KR20210031680A | PGDB_A049500 | PGDB_C008709 | PGDB_AS001244 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A052285 | PGDB_C008709 | PGDB_AS002086 | View |
| Dmax | - | = | 97 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A053528 | PGDB_C008709 | PGDB_AS002581 | View |
| % Degradation | - | = | 90 | % | 10 uM | 24 h | IKZF2 | - | 293GT | KR20210031680A | PGDB_A065247 | PGDB_C008709 | PGDB_AS000887 | View |