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Compound
PGDB_C009991
4 activity records1 related patents
2D structure
Cc1cc(COc2cccc3c2CN([C@H]2CCC(=O)NC2=O)C3=O)ccc1CN1CCN2c3ccc(C#N)cc3OC[C@H]2C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 0.019 | uM | - | — | SALL4 | - | HT-1080 | WO2023025136A1 | PGDB_A020981 | PGDB_C009991 | PGDB_AS001426 | View |
| Dmax | - | = | 63 | % | Concentration series: 0.316 nM, 10 uM | 20 h | SALL4 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A026260 | PGDB_C009991 | PGDB_AS001792 | View |
| DC50 | - | = | 0.11 | nM | - | — | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A034400 | PGDB_C009991 | PGDB_AS001276 | View |
| Dmax | - | = | 94.6 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A048243 | PGDB_C009991 | PGDB_AS000619 | View |