Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C009999
6 activity records1 related patents
2D structure
N#Cc1cnc2c(c1)OC[C@H]1CN(Cc3ccc(COc4cccc5c4CN([C@H]4CCC(=O)NC4=O)C5=O)cc3)CCN21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.064 | nM | - | — | - | - | MM.1S | WO2023025136A1 | PGDB_A040190 | PGDB_C009999 | PGDB_AS001243 | View |
| DC50 | - | > | 10 | uM | - | — | SALL4 | - | HT-1080 | WO2023025136A1 | PGDB_A043869 | PGDB_C009999 | PGDB_AS001426 | View |
| Dmax | - | = | 92.1 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A048327 | PGDB_C009999 | PGDB_AS000619 | View |
| DC50 | - | = | 0.21 | nM | - | — | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A071428 | PGDB_C009999 | PGDB_AS001276 | View |
| Ymin | - | = | 5.2 | % | Concentration series: 0.316 pM, 10 nM | 120 h | - | - | MM.1S | WO2023025136A1 | PGDB_A073259 | PGDB_C009999 | PGDB_AS000580 | View |
| Dmax | - | = | 45.5 | % | Concentration series: 0.316 nM, 10 uM | 20 h | SALL4 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A074897 | PGDB_C009999 | PGDB_AS001792 | View |