Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C010136
5 activity records3 related patents
2D structure
C[C@@H]1[C@@H](Nc2nnc(C3CC4(CCC4)C3)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)c(F)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 11.2 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025090727A1 | PGDB_A052840 | PGDB_C010136 | PGDB_AS001842 | View |
| Ki | - | <= | 0.1 | uM | - | — | - | - | - | WO2024092039 | PGDB_A067305 | PGDB_C010136 | PGDB_AS001899 | View |
| Dmax | - | = | 65 | % | - | 24 h | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A070217 | PGDB_C010136 | PGDB_AS002016 | View |
| Ki | - | <= | 0.1 | uM | - | — | CRBN | CRBN | - | WO2025224262A1 | PGDB_A073872 | PGDB_C010136 | PGDB_AS001844 | View |
| DC50 | - | = | 52.6 | nM | - | — | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A077628 | PGDB_C010136 | PGDB_AS001688 | View |