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Compound
PGDB_C010140
6 activity records2 related patents
2D structure
C[C@@H]1[C@@H](Nc2nnc(C34CC(C(F)(F)F)(C3)C4)o2)CN1c1cc(F)c([C@H]2CCC(=O)NC2=O)c(F)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 62.2 | % | - | 24 h | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A019081 | PGDB_C010140 | PGDB_AS002016 | View |
| Dmax | - | = | 3.7 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025090727A1 | PGDB_A019328 | PGDB_C010140 | PGDB_AS001842 | View |
| DC50 | - | = | 27 | nM | - | — | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A042643 | PGDB_C010140 | PGDB_AS000391 | View |
| DC50 | - | = | 27 | nM | - | — | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A048309 | PGDB_C010140 | PGDB_AS001688 | View |
| Dmax | - | = | 3.7 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025224249A1 | PGDB_A053375 | PGDB_C010140 | PGDB_AS001257 | View |
| Dmax | - | = | 62.2 | % | - | 24 h | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A070485 | PGDB_C010140 | PGDB_AS002358 | View |