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Compound
PGDB_C011639
5 activity records1 related patents
2D structure
C#Cc1cnc([C@H](C)OC)c(-c2c3c4cc(ccc4n2CC)N2CCO[C@@H](C[C@H](NC(=O)[C@H](C(C)C)N(C)C(=O)C4(F)CCN(C(=O)C#CC(C)(C)N(C)C)CC4)C(=O)N4N[C@H](C(=O)OCC(C)(C)C3)C3CC4C3)C2)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | SW620 | WO2025214350A1 | PGDB_A015217 | PGDB_C011639 | PGDB_AS001156 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | NCI-H358 | WO2025214350A1 | PGDB_A030563 | PGDB_C011639 | PGDB_AS001442 | View |
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | HPAC | WO2025214350A1 | PGDB_A061132 | PGDB_C011639 | PGDB_AS002124 | View |
| IC50 | - | = | 100-1000 | nM | - | — | - | - | AsPC-1 | WO2025214350A1 | PGDB_A071873 | PGDB_C011639 | PGDB_AS001410 | View |
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | AGS | WO2025214350A1 | PGDB_A077611 | PGDB_C011639 | PGDB_AS000218 | View |