Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C016410
7 activity records2 related patents
2D structure
Cc1cc(CNC(=O)C(C)(C)c2ccncc2)cc(Cl)c1C1CCC(=O)NC1=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 100-1000 | nM | - | — | CRBN | CRBN | - | WO2025024521A1 | PGDB_A013155 | PGDB_C016410 | PGDB_AS000488 | View |
| Dmax | - | > | 75 | % | Concentration context: various concentrations | 24 h | - | - | CAL-51 | KR20260041885A | PGDB_A015205 | PGDB_C016410 | PGDB_AS000078 | View |
| IC50 | - | = | 0.00987 | uM | - | — | - | - | monocyte-derived macrophages | WO2025024521A1 | PGDB_A040207 | PGDB_C016410 | PGDB_AS000832 | View |
| Dmax | - | > | 75 | % | - | - | NEK7 | CRBN | - | WO2025024521A1 | PGDB_A045145 | PGDB_C016410 | PGDB_AS002165 | View |
| DC50 | - | < | 100 | nM | - | — | NEK7 | CRBN | - | WO2025024521A1 | PGDB_A056060 | PGDB_C016410 | PGDB_AS000280 | View |
| DC50 | - | <= | 100 | nM | - | — | - | - | CAL-51 | KR20260041885A | PGDB_A065224 | PGDB_C016410 | PGDB_AS000761 | View |
| IC50 | - | = | 0.01124 | uM | - | — | - | - | monocyte-derived macrophages | WO2025024521A1 | PGDB_A075994 | PGDB_C016410 | PGDB_AS001704 | View |