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Compound
PGDB_C016641
6 activity records2 related patents
2D structure
O=C1CCC(N2C(=O)c3ccc(C4(F)CCN(Cc5ccccc5)CC4)c4nccc2c34)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | > 100 nM | DC50 < 100 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A017332 | PGDB_C016641 | PGDB_AS000287 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A018137 | PGDB_C016641 | PGDB_AS000499 | View |
| Emax | - | = | 60-95 | % | 10 uM | DC50 > 10000 nM | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A026298 | PGDB_C016641 | PGDB_AS000916 | View |
| DC50 | - | > | 10000 | nM | - | — | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A048934 | PGDB_C016641 | PGDB_AS002445 | View |
| DC50 | - | < | 100 | nM | - | — | - | - | KELLY.2 | WO2022081927A1 | PGDB_A059806 | PGDB_C016641 | PGDB_AS001296 | View |
| DC50 | - | > | 100 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A062993 | PGDB_C016641 | PGDB_AS001223 | View |