Assay

PGDB_AS001790

System: cell_basedTarget: IKZF1Cell line: NCI-H929.11
Assay context summary

Assay context

19 activity records
Assay family% Degradation
Systemcell_based
ReadoutEmax
TargetIKZF1
E3Not specified
Cell lineNCI-H929.11
Technologyluminescence
Activity compounds and values

Activity records

19 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C016633
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A007170PGDB_C016633PGDB_AS001790View
2D structure for PGDB_C016645
Emax->=45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A008459PGDB_C016645PGDB_AS001790View
2D structure for PGDB_C025110
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A013068PGDB_C025110PGDB_AS001790View
2D structure for PGDB_C016646
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A013184PGDB_C016646PGDB_AS001790View
2D structure for PGDB_C016630
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A013630PGDB_C016630PGDB_AS001790View
2D structure for PGDB_C026764
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A014482PGDB_C026764PGDB_AS001790View
2D structure for PGDB_C016634
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A018295PGDB_C016634PGDB_AS001790View
2D structure for PGDB_C026783
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A020344PGDB_C026783PGDB_AS001790View
2D structure for PGDB_C016632
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A023684PGDB_C016632PGDB_AS001790View
2D structure for PGDB_C015421
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A025300PGDB_C015421PGDB_AS001790View
2D structure for PGDB_C016644
Emax->=45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A031816PGDB_C016644PGDB_AS001790View
2D structure for PGDB_C016653
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A036253PGDB_C016653PGDB_AS001790View
2D structure for PGDB_C016648
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A036851PGDB_C016648PGDB_AS001790View
2D structure for PGDB_C026791
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A047142PGDB_C026791PGDB_AS001790View
2D structure for PGDB_C016638
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A049267PGDB_C016638PGDB_AS001790View
2D structure for PGDB_C026784
Emax-<45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A050481PGDB_C026784PGDB_AS001790View
2D structure for PGDB_C016639
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A053722PGDB_C016639PGDB_AS001790View
2D structure for PGDB_C016637
Emax->60%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A065275PGDB_C016637PGDB_AS001790View
2D structure for PGDB_C016636
Emax->=45%-DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM--NCI-H929.11WO2022081927A1PGDB_A072938PGDB_C016636PGDB_AS001790View
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