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Compound
PGDB_C019639
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCC(n5cc(NC(=O)c6ccn7ccc(N8CCOCC8)nc67)c(C(F)F)n5)CC4)c(F)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | Mino | CN116239566A | PGDB_A014113 | PGDB_C019639 | PGDB_AS000456 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | SW620 | CN116239566A | PGDB_A014968 | PGDB_C019639 | PGDB_AS000233 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | CAL-62 | CN116239566A | PGDB_A016165 | PGDB_C019639 | PGDB_AS000175 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | CCRF-CEM | CN116239566A | PGDB_A017909 | PGDB_C019639 | PGDB_AS001036 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | MV-4-11 | CN116239566A | PGDB_A018852 | PGDB_C019639 | PGDB_AS000709 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | Kasumi-1 | CN116239566A | PGDB_A021420 | PGDB_C019639 | PGDB_AS001230 | View |
| IC50 | - | = | 50-100 | nM | - | — | IRAK4 | - | NCI-H166 | CN116239566A | PGDB_A023236 | PGDB_C019639 | PGDB_AS001436 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | Jurkat | CN116239566A | PGDB_A030564 | PGDB_C019639 | PGDB_AS000478 | View |
| IC50 | - | = | 100-500 | nM | - | — | IRAK4 | - | SU-DHL-4 | CN116239566A | PGDB_A035566 | PGDB_C019639 | PGDB_AS002569 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | MM.1R | CN116239566A | PGDB_A076471 | PGDB_C019639 | PGDB_AS000191 | View |