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Compound
PGDB_C024200
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CCN(C(c5ccccc5)c5ccccc5)CC4)c(F)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A013986 | PGDB_C024200 | PGDB_AS002540 | View |
| % Inhibition | - | = | 20-30 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A025076 | PGDB_C024200 | PGDB_AS002133 | View |
| % Inhibition | - | = | 50-60 | % | 10 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A025600 | PGDB_C024200 | PGDB_AS001349 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A035286 | PGDB_C024200 | PGDB_AS001561 | View |
| % Inhibition | - | = | 50-60 | % | 500 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A037538 | PGDB_C024200 | PGDB_AS000568 | View |
| % Inhibition | - | = | 10-20 | % | 10 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A047456 | PGDB_C024200 | PGDB_AS001155 | View |
| % Inhibition | - | = | 40-50 | % | 10 nM | 96 h | IKZF3 | - | CFPAC-1 | WO2025162225A1 | PGDB_A062378 | PGDB_C024200 | PGDB_AS000245 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | CFPAC-1 | WO2025162225A1 | PGDB_A074888 | PGDB_C024200 | PGDB_AS000857 | View |