PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

57 activity records

Assay familyviability

Systemcell_based

Readout% Inhibition

E3Not specified

Cell lineA375

OrganismHomo sapiens

Detection target% Cell viability

Activity compounds and values

Activity records

57 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A007895	PGDB_C024191	PGDB_AS000568	View
% Inhibition	-	=	60-70	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A008653	PGDB_C024214	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A018382	PGDB_C024210	PGDB_AS000568	View
% Inhibition	-	=	50-60	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A020321	PGDB_C024203	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A021192	PGDB_C024221	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A022262	PGDB_C024241	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A023060	PGDB_C024220	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A023512	PGDB_C024225	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A027777	PGDB_C024209	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A027995	PGDB_C024244	PGDB_AS000568	View
% Inhibition	-	=	80-100	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A028094	PGDB_C024215	PGDB_AS000568	View
% Inhibition	-	=	60-70	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A028243	PGDB_C024240	PGDB_AS000568	View
% Inhibition	-	=	50-60	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A030591	PGDB_C024198	PGDB_AS000568	View
% Inhibition	-	=	60-70	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A032525	PGDB_C024213	PGDB_AS000568	View
% Inhibition	-	=	60-70	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A034495	PGDB_C024226	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A035109	PGDB_C024204	PGDB_AS000568	View
% Inhibition	-	=	60-70	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A036237	PGDB_C024239	PGDB_AS000568	View
% Inhibition	-	=	50-60	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A036676	PGDB_C024218	PGDB_AS000568	View
% Inhibition	-	=	40-50	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A036822	PGDB_C024227	PGDB_AS000568	View
% Inhibition	-	=	50-60	%	500 nM	96 h	IKZF3	-	A375	WO2025162225A1	PGDB_A036936	PGDB_C024246	PGDB_AS000568	View

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