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Compound
PGDB_C024210
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CC5CN(C(c6ccc(Cl)cc6)c6ccc(Cl)cc6)CC5C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A018382 | PGDB_C024210 | PGDB_AS000568 | View |
| % Inhibition | - | = | 10-20 | % | 10 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A024608 | PGDB_C024210 | PGDB_AS001349 | View |
| % Inhibition | - | = | 60-70 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A030290 | PGDB_C024210 | PGDB_AS002540 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A032046 | PGDB_C024210 | PGDB_AS002133 | View |