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Compound
PGDB_C024212
6 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CCC5(CC4)CN(C(=O)c4ccccc4-c4ccc(Cl)cc4)C5)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 70-80 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A015698 | PGDB_C024212 | PGDB_AS002133 | View |
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A028856 | PGDB_C024212 | PGDB_AS001902 | View |
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A041879 | PGDB_C024212 | PGDB_AS002324 | View |
| % Inhibition | - | = | 80-100 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A061189 | PGDB_C024212 | PGDB_AS002540 | View |
| % Inhibition | - | = | 50-60 | % | 500 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A062124 | PGDB_C024212 | PGDB_AS000568 | View |
| % Inhibition | - | = | 30-40 | % | 10 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A066660 | PGDB_C024212 | PGDB_AS001349 | View |