Assay

PGDB_AS001024

System: cell_basedTarget: IKZF1Cell line: NCI-H929
Assay context summary

Assay context

10 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF1
E3Not specified
Cell lineNCI-H929
OrganismHomo sapiens
TechnologyWestern_blot
Detection targetprotein_degradation
Activity compounds and values

Activity records

10 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C025599
DC50-=0.081nM-—--NCI-H929EP4685141A1PGDB_A008886PGDB_C025599PGDB_AS001024View
2D structure for PGDB_C025624
DC50-=0.37nM-—--NCI-H929EP4685141A1PGDB_A009501PGDB_C025624PGDB_AS001024View
2D structure for PGDB_C025597
DC50-=0.31nM-—--NCI-H929EP4685141A1PGDB_A021792PGDB_C025597PGDB_AS001024View
2D structure for PGDB_C025601
DC50-=0.23nM-—--NCI-H929EP4685141A1PGDB_A037144PGDB_C025601PGDB_AS001024View
2D structure for PGDB_C025619
DC50-=0.98nM-—--NCI-H929EP4685141A1PGDB_A040140PGDB_C025619PGDB_AS001024View
2D structure for PGDB_C025625
DC50-=0.34nM-—--NCI-H929EP4685141A1PGDB_A044626PGDB_C025625PGDB_AS001024View
2D structure for PGDB_C025616
DC50-=0.1nM-—--NCI-H929EP4685141A1PGDB_A044732PGDB_C025616PGDB_AS001024View
2D structure for PGDB_C025617
DC50-=0.077nM-—--NCI-H929EP4685141A1PGDB_A051678PGDB_C025617PGDB_AS001024View
2D structure for PGDB_C025600
DC50-=0.38nM-—--NCI-H929EP4685141A1PGDB_A057604PGDB_C025600PGDB_AS001024View
2D structure for PGDB_C025615
DC50-=8.86nM-—--NCI-H929EP4685141A1PGDB_A074731PGDB_C025615PGDB_AS001024View
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