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Compound
PGDB_C025813
5 activity records1 related patents
2D structure
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCN(Cc2cc3c(cc2F)C(=O)N(C2CCC(=O)NC2=O)C3)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 1000-5000 | nM | - | — | BTK | - | THP-1 | CN116239566A | PGDB_A011017 | PGDB_C025813 | PGDB_AS000486 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | CCRF-CEM | CN116239566A | PGDB_A032065 | PGDB_C025813 | PGDB_AS000469 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | MM.1S | CN116239566A | PGDB_A056292 | PGDB_C025813 | PGDB_AS002551 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | MDA-MB-231 | CN116239566A | PGDB_A072849 | PGDB_C025813 | PGDB_AS001770 | View |
| IC50 | - | = | 1000-5000 | nM | - | — | BTK | - | Kasumi-1 | CN116239566A | PGDB_A073122 | PGDB_C025813 | PGDB_AS000510 | View |