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Compound
PGDB_C025954
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(ccc(CN4CCC(n5cc(NC(=O)c6cnn7ccc(N8CCOCC8)nc67)c(C(F)F)n5)CC4)c3F)C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-500 | nM | - | — | IRAK4 | - | SU-DHL-4 | CN116239566A | PGDB_A013698 | PGDB_C025954 | PGDB_AS002569 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | MV-4-11 | CN116239566A | PGDB_A014526 | PGDB_C025954 | PGDB_AS000709 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | SW620 | CN116239566A | PGDB_A022892 | PGDB_C025954 | PGDB_AS000233 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | Jurkat | CN116239566A | PGDB_A024041 | PGDB_C025954 | PGDB_AS000478 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | Mino | CN116239566A | PGDB_A042253 | PGDB_C025954 | PGDB_AS000456 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | CCRF-CEM | CN116239566A | PGDB_A044379 | PGDB_C025954 | PGDB_AS001036 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | Kasumi-1 | CN116239566A | PGDB_A049498 | PGDB_C025954 | PGDB_AS001230 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | MM.1R | CN116239566A | PGDB_A052888 | PGDB_C025954 | PGDB_AS000191 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | CAL-62 | CN116239566A | PGDB_A061123 | PGDB_C025954 | PGDB_AS000175 | View |
| IC50 | - | = | 100-500 | nM | - | — | IRAK4 | - | NCI-H166 | CN116239566A | PGDB_A076590 | PGDB_C025954 | PGDB_AS001436 | View |