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Compound
PGDB_C026265
6 activity records2 related patents
2D structure
Cn1ncc2ccc(C(C)(C)C(=O)NCc3cc(Cl)c(C4CCC(=O)NC4=O)c(Cl)c3)cc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | <= | 100 | nM | - | — | - | - | CAL-51 | KR20260041885A | PGDB_A017989 | PGDB_C026265 | PGDB_AS002572 | View |
| Dmax | - | > | 75 | % | Concentration series: 1 uM, 0.05 nM | 24 h | - | - | CAL-51 | KR20260041885A | PGDB_A033906 | PGDB_C026265 | PGDB_AS001446 | View |
| Dmax | - | > | 75 | % | - | - | NEK7 | CRBN | - | WO2025024521A1 | PGDB_A035708 | PGDB_C026265 | PGDB_AS002165 | View |
| EC50 | - | < | 100 | nM | - | — | CRBN | CRBN | - | WO2025024521A1 | PGDB_A047902 | PGDB_C026265 | PGDB_AS000488 | View |
| DC50 | - | < | 100 | nM | - | — | NEK7 | CRBN | - | WO2025024521A1 | PGDB_A061964 | PGDB_C026265 | PGDB_AS000280 | View |
| EC50 | - | <= | 100 | nM | - | — | - | - | - | KR20260041885A | PGDB_A073875 | PGDB_C026265 | PGDB_AS001290 | View |