PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000111

NameALK

Gene symbolALK

Protein nameALK tyrosine kinase receptor

UniProt IDQ9UM73

Roledegradation_target | primary_target

Compounds232

Activity records730

Assays14

Patents3

Activity compounds and values

Activity records

730 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A007010	PGDB_C012312	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A007242	PGDB_C012275	PGDB_AS002152	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A007488	PGDB_C012321	PGDB_AS000738	View
Emax	-	>	120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A007573	PGDB_C012421	PGDB_AS001094	View
Emax	-	=	50-120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A007649	PGDB_C012407	PGDB_AS001094	View
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A007728	PGDB_C012380	PGDB_AS002152	View
Emax	-	>	120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A007730	PGDB_C012471	PGDB_AS001094	View
Emax	-	>	120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A007769	PGDB_C012450	PGDB_AS001094	View
Emax	-	>	120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A007980	PGDB_C012439	PGDB_AS001094	View
Emax	-	=	50-120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A008220	PGDB_C012342	PGDB_AS001094	View
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008248	PGDB_C012362	PGDB_AS000738	View
EC50	-	>	1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008308	PGDB_C012418	PGDB_AS000738	View
Emax	-	>	120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A008497	PGDB_C012301	PGDB_AS001094	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008697	PGDB_C012454	PGDB_AS000738	View
EC50	-	>	1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008722	PGDB_C012363	PGDB_AS000738	View
Emax	-	=	50-120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A008764	PGDB_C012278	PGDB_AS001769	View
Emax	-	=	50-120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A008890	PGDB_C012462	PGDB_AS001094	View
Emax	-	>	120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A008961	PGDB_C012406	PGDB_AS001094	View
EC50	-	<	10	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008993	PGDB_C012320	PGDB_AS002152	View
Emax	-	=	50-120	%	-	2 h	ALK	CRBN	-	WO2026015344A1	PGDB_A009123	PGDB_C012330	PGDB_AS001094	View

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