Assay

PGDB_AS000521

System: cell_basedTarget: IKZF3Cell line: NCI-H929
Assay context summary

Assay context

10 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF3
E3Not specified
Cell lineNCI-H929
OrganismHomo sapiens
Detection targetprotein_degradation
Activity compounds and values

Activity records

10 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C025597
DC50-=0.12nM-—IKZF3-NCI-H929CA3286762A1PGDB_A014395PGDB_C025597PGDB_AS000521View
2D structure for PGDB_C025600
DC50-=0.19nM-—IKZF3-NCI-H929CA3286762A1PGDB_A014746PGDB_C025600PGDB_AS000521View
2D structure for PGDB_C025615
DC50-=0.22nM-—IKZF3-NCI-H929CA3286762A1PGDB_A017797PGDB_C025615PGDB_AS000521View
2D structure for PGDB_C025619
DC50-=0.075nM-—IKZF3-NCI-H929CA3286762A1PGDB_A023982PGDB_C025619PGDB_AS000521View
2D structure for PGDB_C025601
DC50-=0.12nM-—IKZF3-NCI-H929CA3286762A1PGDB_A033768PGDB_C025601PGDB_AS000521View
2D structure for PGDB_C025599
DC50-=0.05nM-—IKZF3-NCI-H929CA3286762A1PGDB_A040658PGDB_C025599PGDB_AS000521View
2D structure for PGDB_C025616
DC50-=0.056nM-—IKZF3-NCI-H929CA3286762A1PGDB_A053318PGDB_C025616PGDB_AS000521View
2D structure for PGDB_C021277
DC50-=0.093nM-—IKZF3-NCI-H929CA3286762A1PGDB_A056752PGDB_C021277PGDB_AS000521View
2D structure for PGDB_C025617
DC50-=0.036nM-—IKZF3-NCI-H929CA3286762A1PGDB_A070716PGDB_C025617PGDB_AS000521View
2D structure for PGDB_C021276
DC50-=0.16nM-—IKZF3-NCI-H929CA3286762A1PGDB_A075368PGDB_C021276PGDB_AS000521View
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