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Compound
PGDB_C002550
8 activity records1 related patents
2D structure
Cc1ccc(C2=C(CN3CCN(Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)CCC(C)(C)C2)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A010535 | PGDB_C002550 | PGDB_AS000668 | View |
| IC50 | - | = | 5-10 | nM | - | — | - | - | CCRF-CEM | WO2024032689A1 | PGDB_A012440 | PGDB_C002550 | PGDB_AS001396 | View |
| IC50 | - | = | 5-10 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A020496 | PGDB_C002550 | PGDB_AS001703 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A041117 | PGDB_C002550 | PGDB_AS000176 | View |
| IC50 | - | = | 0.66 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A042755 | PGDB_C002550 | PGDB_AS000095 | View |
| IC50 | - | = | 5-10 | nM | - | — | - | - | Mino | WO2024032689A1 | PGDB_A067757 | PGDB_C002550 | PGDB_AS001319 | View |
| IC50 | - | = | 50-100 | nM | - | — | - | - | Daudi | WO2024032689A1 | PGDB_A069945 | PGDB_C002550 | PGDB_AS002481 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A073615 | PGDB_C002550 | PGDB_AS002239 | View |