PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

55 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetGSPT1

E3Not specified

Cell lineJurkat

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

55 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	50-70	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A009275	PGDB_C001317	PGDB_AS001008	View
% Degradation	-	=	70-90	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A010367	PGDB_C001336	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A011384	PGDB_C001349	PGDB_AS001008	View
% Degradation	-	=	70-90	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A011460	PGDB_C001344	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A011515	PGDB_C001321	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A012657	PGDB_C001348	PGDB_AS001008	View
% Degradation	-	=	30-50	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A012760	PGDB_C001350	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A013469	PGDB_C001340	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A014239	PGDB_C001302	PGDB_AS001008	View
% Degradation	-	=	30-50	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A014807	PGDB_C001338	PGDB_AS001008	View
% Degradation	-	=	70-90	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A014841	PGDB_C001342	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A015000	PGDB_C001355	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A021833	PGDB_C001324	PGDB_AS001008	View
% Degradation	-	=	30-50	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A023074	PGDB_C001334	PGDB_AS001008	View
% Degradation	-	=	50-70	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A023591	PGDB_C001328	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A024236	PGDB_C001346	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A024406	PGDB_C001303	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A026976	PGDB_C001325	PGDB_AS001008	View
% Degradation	-	=	30-50	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A028910	PGDB_C001352	PGDB_AS001008	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A029259	PGDB_C001358	PGDB_AS001008	View

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